Decision-making and problem solving in complex PCI: interactive case-based learning

Angela McInerney is an Interventional Cardiologist at University Hospital Galway, Ireland. Following completion of her basic cardiology training in Ireland she was awarded the Brian McGovern Travelling Fellowship grant from the Irish Board for Cardiology Training in 2018 which allowed her to start her interventional fellowship in Hospital Clínico San Carlos, Madrid, Spain. Following two years of coronary training including complex PCI, she was awarded an European Society of Cardiology Fellowship Training Grant and completed a further year of structural intervention also in Clínico San Carlos, Madrid. Her specialist interests are in intracoronary imaging, intracoronary physiology, calcium modification techniques and complex PCI. She has been keenly involved in various research projects pertaining to intracoronary physiology and intravascular imaging having authored and co-authored a number of research articles as well as review articles and book chapters on these topics. During her fellowship she also regularly partook in the preparation and delivery of educational courses in Clínico San Carlos and values the educational aspect of her role as a Consultant Interventional Cardiologist.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >700 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 100) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Prof. Mehilli is the Chief of the First Medical Clinic (Cardiology/Pulmonology/Intensive Medicine) at the Hospital Landshut-Achdorf and Professor for Cardiology at the Ludwig-Maximilians University, Munich, Germany. Before her appointment as Clinic Chief in September 2020, she was for 10 years director of the catheterisation laboratories first at the Deutsches Herzzentrum thereafter at the LMU University Clinic in Munich and was responsible for both coronary and structural invasive programs. With more than 6000 PCIs and more than 2000 catheter-based valvular procedures, she is one of the most experienced operators in Germany Prof Mehilli spend nearly 20 years with clinical research, first as co-founder and co-director of the well-known ISAResearch Zentrum, thereafter as leader of the working group Minimal-Invasive Cardiology at the LMU Clinic and Principal Investigator at the German Center for Cardiovascular Research (DZHK) . She has led many national and international multicentre trials and authored a multitude of high-ranking publications with a total impact factor of more than 4000. She is member of various boards and cardiologic societies – AGIK, EAPCI, DGK, ESC, Women-EAPCI as well as associate editor for medical journals as European Heart Journal, Journal American College of Cardiology and EuroIntervention.

Dr Justin Davies is a board member of Monaco Cardio at the Princess Grace Hospital, Monaco, and an interventional cardiologist with over 15 years of experience as a leading educator in the field. His clinical and academic career was established at Hammersmith Hospital, Imperial College London, where he built an international reputation for innovation in cardiovascular medicine. Over the course of his career, he has successfully mentored 15 PhD students, published more than 500 peer-reviewed papers — including landmark studies in the New England Journal of Medicine and The Lancet — and holds 20 patents in cardiovascular medicine and technology. He was the co-principal investigator of the DEFINE-FLAIR study, which helped establish iFR (Instantaneous Wave-Free Ratio), a diagnostic technique he invented, as a globally adopted standard in coronary physiology. His work reflects a unique blend of scientific innovation, academic leadership, and clinical excellence. In addition to his research and academic commitments, Justin is CEO of Cerebria AI, where he leads the development of next-generation AI-powered cardiovascular imaging and physiology tools. Under his leadership, Cerebria AI is advancing cutting-edge solutions that integrate artificial intelligence with frontline cardiology to enhance clinical decision-making and patient outcomes. Combining deep clinical expertise with entrepreneurial vision, he continues to guide international ventures through funding, regulatory pathways, and commercialization, while remaining committed to transforming cardiovascular care on a global scale.

Prof. Byrne graduated from University College Dublin, Ireland and completed his PhD in Medical Life Science and Technology at the Technical University Munich, Germany. Research awards received include the ESC Atherothrombosis Research Fellowship (2008), the TCT Thomas J. Linnemeier Young Investigator Award (2009) and the Andreas Grüntzig Research Prize of the German Cardiac Society (2016). Leadership roles include Deputy Editor at EuroIntervention and board member of EAPCI and Chair of its Patient Initiatives Committee.