An Introduction to iFR: Concepts, Principals, and Limitations - Dr. Justin Davies
Summary
Dr Justin Davies, Consultant Cardiologist, Imperial College London, UK
Dr Justin Davies introduces iFR (Instantaneous Wave-free Ratio), and discuses the concepts, principals and limitations....
Summary
Dr Justin Davies, Consultant Cardiologist, Imperial College London, UK
Dr Justin Davies introduces iFR (Instantaneous Wave-free Ratio), and discuses the concepts, principals and limitations.
Key learning points:-
- 1. Diastole provides the most sensitive phase of the cardiac cycle to identify stenosis severity
- 2. Pressure is proportional to flow when resistance is stable
- 3. In FFR resistance is stabilised using powerful vasodilator such as adenosine
- 4. In iFR resistance is stabilised by analysing the cardiac cycle over the diastolic Wave-free Period, without the need for drug administration
- 5. Pharmacological hyperaemia differs markedly from exercise induced hyperaemia
- 6. iFR provides a direct measure of the vasodilatory effect on the coronary microcirculation
Simple Education, is a leading provider of coronary physiology and intracoronary imaging courses to aid treatment of complex coronary artery disease.
Speakers
Justin Davies
Speaker
Dr Justin Davies is a honorary interventional cardiologist at Hammersmith Hospital, Imperial... Dr Justin Davies is a honorary interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents, he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).
