Guiding and optimizing PCI with imaging and physiology

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >700 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 100) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Jiang Ming Fam is a Senior Consultant in the Department of Cardiology at the National Heart Centre, Singapore (NHCS). He completed his advanced specialist training in the field of cardiology following which he completed his advanced subspecialty training in Interventional Cardiology in Thorax Centre, Erasmus Medical Centre, Rotterdam, the Netherlands in June 2015. He defended his PhD thesis titled “Bioresorbable polymer coated metallic stents and fully bioresorbable scaffolds: Benefits and limitations in different coronary lesion subsets -Clinical and intravascular imaging results” in May 2018. He is currently a full time interventional cardiologist and has participated in interventional conferences such as ASIA-PCR and NHCS CTO Live as a live case operator since 2014. Dr Fam is actively involved in education and research. He is a lecturer and module coordinator in the Singapore Polytechnic Diploma in Biomedical Science (Cardiac Technology Course) and is part of the faculty of DUKE-NUS Medical School, Lee Kong Chian Medical School and the Singhealth residency program. His research interests include intravascular physiology and imaging as well as clinical outcomes in patients with percutaneous coronary intervention in complex lesion subsets such as bifurcation and left main intervention. He is an active investigator in multiple clinical trials and has presented his research findings in local and international conferences. He is the first/coauthor of numerous research papers in local and international peer reviewed journals and is also an ad hoc reviewer for various journals in interventional and general cardiology.

Dr Justin Davies is a board member of Monaco Cardio at the Princess Grace Hospital, Monaco, and an interventional cardiologist with over 15 years of experience as a leading educator in the field. His clinical and academic career was established at Hammersmith Hospital, Imperial College London, where he built an international reputation for innovation in cardiovascular medicine. Over the course of his career, he has successfully mentored 15 PhD students, published more than 500 peer-reviewed papers — including landmark studies in the New England Journal of Medicine and The Lancet — and holds 20 patents in cardiovascular medicine and technology. He was the co-principal investigator of the DEFINE-FLAIR study, which helped establish iFR (Instantaneous Wave-Free Ratio), a diagnostic technique he invented, as a globally adopted standard in coronary physiology. His work reflects a unique blend of scientific innovation, academic leadership, and clinical excellence. In addition to his research and academic commitments, Justin is CEO of Cerebria AI, where he leads the development of next-generation AI-powered cardiovascular imaging and physiology tools. Under his leadership, Cerebria AI is advancing cutting-edge solutions that integrate artificial intelligence with frontline cardiology to enhance clinical decision-making and patient outcomes. Combining deep clinical expertise with entrepreneurial vision, he continues to guide international ventures through funding, regulatory pathways, and commercialization, while remaining committed to transforming cardiovascular care on a global scale.